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LEUKEMIA
LEUKEMIA Means “white blood” WBC count soars to as high as 500,000-1 million/cubic mm Form of cancer and usually proves fatal The human T-cell leukemia - lymphoma virus -1 (HTLV-1) is strongly associated with leukemia 2 major types: 1. Myeloid - abnormal production of granulocytes by red bone marrow 2. Lymphoid - increased formation of lymphocytes in lymph nodes Acute lymphoid leukemia is the most common cancerous condition in children Greatest success in treating this form of leukemia The type of leukocyte involved differentiates the varieties Granulocytic, lymphocytic and monocytic Leukemias are classified as acute or chronic Acute - appears suddenly, progresses rapidly - death occurs in a few months – usually affect children Chronic - begins more slowly - without treatment may live 3 years –seen more in elderly WBCs are formed so rapidly in bone that immature RBCs and platelets are starved out Leads to severe anemia and bleeding problems One common cause of death is internal hemorrhaging, especially cerebral WBCs plug blood vessels in brain, heart, lungs and kidney Leukemic cells from bone marrow may invade other areas of bone weakening its structure and stimulating pain receptors Leukemia cells are usually abnormal and often have little phagocytic ability Most frequent cause death is uncontrolled infection due to lack of normal mature WBCs Causes - radiation, benzene and other chemicals Partial or complete remissions may be induced, some lasting as long as 15 years
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