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Blood Facts Rh SYSTEM
Rh SYSTEM Consists of over 40 antigens found on RBCs Named after the Rhesus monkey in which it was 1st identified Major Rh types include Rho, Rh’, and Rh” factors Most are weak and seldom elicit antibody production Rho factor is strongest = antigen D If antigen is present on RBC membrane, the person is Rh+ 85% of American Caucasians and 88% of American blacks 98% of Japanese and Chinese One major difference between ABO and Rh blood systems is that there are no Rh antibodies unless there was previous contact with Rh antigens Anti - Rh antibodies appear in the blood of an Rh- person provided Rh+ RBCs entered his circulation Generally there are no ill effects due to the 1st transfusion of Rh+ blood into an Rh- person because it takes time to form antibodies But if another Rh+ transfusion is given, serious agglutination may occur If an Rh- woman carried an Rh+ fetus Some of its blood may enter her circulation causing her plasma to develop anti-D antibodies – the greatest blood transfer occurs at delivery These may diffuse across placenta and agglutinate blood of the fetus in future pregnancies As a result fetus may die or be born with a severe blood disease called erythroblastosis fetalis - named because of relese of many immature RBCs called erythroblasts Estimate in U.S. that 1 child in 10 is an Rh+ child of an Rh- mother, but only 1 in 500 is likely to develop erythroblastosis fetalis (a form of hemolytic anemia due to massive destruction of baby’s RBCs) Also characterized by: 90% of cases caused by the production of anti-Rh antibodies in the mother’s blood 10% of cases due to ABO incompatibilities - other blood groups such as Kell, Kidd and Duffy groups are frequently implicated RhoGAM [Rho (D) Immune Globulin] New treatment in 1970’s Commercial preparation designed to suppress maternal antibody production Prepared from plasma of a person with a high concentration of Rh antibodies Flooding the mother’s system with antibodies relieves her own immune system of the stimulus to manufacture antibodies on its own The injected antibodies disappear after a while - hence the need for retreatment after each pregnancy Administer intramuscularly Need not be admininistered during pregnancy, protection is accomplished if given within 72 hours after delivery Must be given following each pregnancy Since Rh antigens are developed about 6th week in fetal life, RhoGAM should also be given to Rh- mothers after miscarriages or abortions
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Rare Blood Types in Alphabetical per state in USA, Rare Blood Types in .Rare Blood Types in Alabama, Rare Blood Types in Alaska, Rare Blood Types in Arizona, Rare Blood Types in Arkansas, Rare Blood Types in California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Georgia, Hawaii, Idaho, Illinois, Rare Blood in 5 Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Rare Blood in Maryland, Rare Types in Massachusetts, Rare Types in Michigan, Rare Types in Minnesota, .25 Mississippi, Missouri, Montana, Nebraska, Nevada, Rare Types in New Hampshire, Rare Types in New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Rare Types in Oklahoma, Oregon, Pennsylvania, Rare Types in Rhode Island, Rare Types in South Carolina, Rare Types in South Dakota, Rare Types in Tennessee, Rare Types in Texas, Rare Types in Utah, Rare Types in Vermont, Rare Types in Virginia, Washington, West Virginia, Rare Types in Wisconsin, Rare Types in Wyoming, Alabama, Birmingham , Gadsden, Huntsville, Mobile, Montgomery , Selma, Tuscaloosa, Alaska, Anchorage, Barrow , Fairbanks, Juneau, Ketchikan, Nome, Sitka, Skagway, Valdez, Arizona, Flagstaff, Mesa, Phoenix, Tempe, Tucson, Yuma, Arkansas, Fort Smith , Little Rock, Texarkana , California , Alameda , Anaheim, Bakersfield , Berkeley , Beverly Hills, Compton , Escondido, Eureka, Fremont , Fresno, Garden Grove, Lodi, Long Beac. RareBloodTypes.Org is online information website to create awareness about "rare blood types". As a policy matter we do not share information provided by "rare blood type donors" online. © 2008, 2009, 2010, 2011 RareBloodTypes.Org. All Rights Reserved
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